Details of Metabolite

General Information of MET (ID: META00914)
Name (E)-4-Hexen-1-ol
Synonyms   Click to Show/Hide Synonyms of This Metabolite
(Z)-Hex-2-en-1-ol; (Z)-Hex-3-en-1-ol; (Z)-Hex-4-en-1-ol; (e)-4-Hexenol; Hex-4-en-1-ol; trans-4-Hexenol
Source Aliphatic acyclic compounds
Structure Type   Fatty alcohols  (Click to Show/Hide the Complete Structure Type Hierarchy)
Lipids and lipid-like molecules
Fatty Acyls
Fatty alcohols
PubChem CID
5365589
HMDB ID
HMDB0031502
Formula
C6H12O
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5365589"></iframe>
3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
FooDB ID
FDB011532
ChemSpider ID
4517556
Physicochemical Properties Molecular Weight 100.16 Topological Polar Surface Area 20.2
XlogP 1.2 Complexity 48.1
Heavy Atom Count 7 Rotatable Bond Count 3
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 1
Function
(Z)-4-Hexen-1-ol is found in fruits. (Z)-4-Hexen-1-ol is a constituent of bananas.
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Pore-forming PNC peptide (PNC)
            Cellular tumor antigen p53 (TP53) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockout of TP53
                      Induced Change (E)-4-Hexen-1-ol concentration: increase (Log2 FC=1.02)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Colon cancer [ICD-11: 2B90]
                      Details It is reported that knockout of TP53 leads to the increase of (E)-4-hexen-1-ol levels compared with control group.
References
1 Integrative omics analysis of p53-dependent regulation of metabolism. FEBS Lett. 2018 Feb;592(3):380-393.

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