| General Information of MET (ID: META00849) |
| Name |
N-a-Acetyl-L-arginine
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| Synonyms |
Click to Show/Hide Synonyms of This Metabolite
Acetyl arginine; N(2)-Acetyl-L-arginine; N-Ac-L-arg-OH; N-Acetyl-L-arginine; N-alpha-Acetyl-L-arginine; N-alpha-Acetylarginine; N-alpha-L-Acetyl-arginine; N2-Acetyl-L-arginine
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| Source |
Endogenous;Food;Drug
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| Structure Type |
Amino acids, peptides, and analogues (Click to Show/Hide the Complete Structure Type Hierarchy)
Organic acids and derivatives
Carboxylic acids and derivatives
Amino acids, peptides, and analogues
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| PubChem CID |
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| HMDB ID |
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| Formula |
C8H16N4O3
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| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=67427"></iframe>
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3D MOL
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2D MOL
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Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
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| DrugBank ID |
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| ChEBI ID |
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| FooDB ID |
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| ChemSpider ID |
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| Physicochemical Properties |
Molecular Weight |
216.24 |
Topological Polar Surface Area |
131 |
| XlogP |
-1.7 |
Complexity |
261 |
| Heavy Atom Count |
15 |
Rotatable Bond Count |
6 |
| Hydrogen Bond Donor Count |
4 |
Hydrogen Bond Acceptor Count |
4 |
| Function |
N-alpha-Acetylarginine is one of the guanidino compounds found elevated in the serum of an hemodialyzed renal insufficient (uremic) pediatric population. N-alpha-acetylarginine serum levels (and other guanidino compounds) were elevated of all the hyperargininemic patients are higher than the normal range. Untreated hyperargininemic patients have the highest guanidino compound levels in cerebrospinal fluid. N-alpha-acetylarginine increases in urine hyperargininemic patients. During a low-arginine diet, together with sodium benzoate therapy, there was a marked decrease in plasma N-alpha-acetylarginine.
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Regulatory Network
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Induced Change
