| General Information of MET (ID: META00823) |
| Name |
3-Nitrotyrosine
|
| Synonyms |
Click to Show/Hide Synonyms of This Metabolite
(2S)-2-Amino-3-(4-hydroxy-3-nitrophenyl)propanoate; (2S)-2-Amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid; 3-Mononitrotyrosine; 3-Nitrotyrosine; 3-Nitrotyrosine, (DL)-isomer; 3-Nitrotyrosine, (L)-isomer; 5-Nitrotyrosine; L-3-Nitrotyrosine; META-nitro-tyrosine; Nitro-tyrosine; Nitrotyrosine; m-Nitrotyrosine
|
| Source |
Endogenous;Food;Drug
|
| Structure Type |
Amino acids, peptides, and analogues (Click to Show/Hide the Complete Structure Type Hierarchy)
Organic acids and derivatives
Carboxylic acids and derivatives
Amino acids, peptides, and analogues
|
| PubChem CID |
|
| HMDB ID |
|
| Formula |
C9H10N2O5
|
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=65124"></iframe>
|
 |
|
3D MOL
|
2D MOL
|
|
Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
|
| DrugBank ID |
|
| ChEBI ID |
|
| FooDB ID |
|
| ChemSpider ID |
|
| METLIN ID |
|
| Physicochemical Properties |
Molecular Weight |
226.19 |
Topological Polar Surface Area |
129 |
| XlogP |
-2 |
Complexity |
278 |
| Heavy Atom Count |
16 |
Rotatable Bond Count |
3 |
| Hydrogen Bond Donor Count |
3 |
Hydrogen Bond Acceptor Count |
6 |
| Function |
3-Nitrotyrosine (NTyr) is formed in vivo in tissue or blood proteins after exposure to nitrosating and/or nitrating agents such as tetranitromethane. Reactive nitrogen species such as peroxynitrite can nitrate specific amino acids, whether free or protein bound, and 3-nitrotyrosine is believed to be one marker of this reaction.
|
|
Regulatory Network
|
|
|
|
|
|
|
|
|
click to show the details of this protein
Induced Change
