| General Information of MET (ID: META00812) |
| Name |
Fucose 1-phosphate
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| Synonyms |
Click to Show/Hide Synonyms of This Metabolite
6-Deoxy-1-O-phosphono-beta-L-galactopyranose; 6-Deoxy-L-galactose 1-phosphate; 6-Deoxy-L-galactose 1-phosphoric acid; Fucopyranosyl phosphate; Fucopyranosyl phosphoric acid; Fucose 1-phosphate; Fucose 1-phosphoric acid; L-Fucopyranose 1-(dihydrogen phosphate); L-Fucose 1-phosphate; L-Fucose-1-phosphate; b-L-Fucose 1-phosphate; b-L-Fucose 1-phosphoric acid; beta-L-Fucopyranosyl dicyclohexylammonium phosphate; beta-L-Fucose 1-phosphate
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| Source |
Endogenous;Food
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| Structure Type |
Carbohydrates and carbohydrate conjugates (Click to Show/Hide the Complete Structure Type Hierarchy)
Organic oxygen compounds
Organooxygen compounds
Carbohydrates and carbohydrate conjugates
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| PubChem CID |
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| HMDB ID |
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| Formula |
C6H13O8P
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| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=65369"></iframe>
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3D MOL
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2D MOL
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Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
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| KEGG ID |
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| ChEBI ID |
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| FooDB ID |
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| Physicochemical Properties |
Molecular Weight |
244.14 |
Topological Polar Surface Area |
137 |
| XlogP |
-3.2 |
Complexity |
264 |
| Heavy Atom Count |
15 |
Rotatable Bond Count |
2 |
| Hydrogen Bond Donor Count |
5 |
Hydrogen Bond Acceptor Count |
8 |
| Function |
Fucose 1-phosphate (CAS: 16562-58-6) belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphate group linked to the carbohydrate unit. Fucose 1-phosphate is an intermediate in the reversible synthesis of GDP-L-fucose catalyzed by the enzyme guanosine triphosphate fucose pyrophosphorylase (GFPP, EC 2.7.7.30). The reversible reaction is magnesium-dependent, although the enzyme is partially active when cobalt or manganese is substituted. The reaction is unusual in that, of the four canonical nucleoside triphosphates, only guanosine can be utilized efficiently to form a nucleotide-sugar. Free cytosolic fucose is phosphorylated by L-fucokinase (EC 2.7.1.52) to form fucose-1-phosphate in the salvage pathway of GDP-L-fucose.
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Regulatory Network
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Induced Change
