Details of Metabolite

General Information of MET (ID: META00509)
Name Inosine diphosphate
Synonyms   Click to Show/Hide Synonyms of This Metabolite
5'-IDP, Inosine 5'-(trihydrogen diphosphate), Inosine 5'-(trihydrogen pyrophosphate), Inosine 5'-diphosphate, Inosine 5'-pyrophosphate, 'Inosine diphosphate; Diphosphate, inosine; Inosine pyrophosphate; Pyrophosphate, inosine; Riboxin; Riboxine
Source Endogenous;Escherichia Coli Metabolite;Yeast Metabolite;Food
Structure Type   Purine ribonucleotides  (Click to Show/Hide the Complete Structure Type Hierarchy)
Nucleosides, nucleotides, and analogues
Purine nucleotides
Purine ribonucleotides
PubChem CID
644173
HMDB ID
HMDB0003335
Formula
C10H14N4O11P2
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
KEGG ID
C00104
ChEBI ID
17808
FooDB ID
FDB023146
ChemSpider ID
559208
METLIN ID
6892
Physicochemical Properties Molecular Weight 428.1859 Topological Polar Surface Area N.A.
XlogP N.A. Complexity N.A.
Heavy Atom Count N.A. Rotatable Bond Count N.A.
Hydrogen Bond Donor Count N.A. Hydrogen Bond Acceptor Count N.A.
Function
IDP is an inosine nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Mitochondrial carrier (MC)
            Solute carrier family 25 member 36 (SLC25A36) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Recombinant protein addition of SLC25A36
                      Induced Change Inosine diphosphate concentration: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that recombinant protein addition of SLC25A36 leads to the increase of inosine diphosphate levels compared with control group.
References
1 The human SLC25A33 and SLC25A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters. J Biol Chem. 2014 Nov 28;289(48):33137-48.

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